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Dengue
An acute febrile disease transmitted by the bite of AEDES mosquitoes infected with DENGUE VIRUS. It is self-limiting and characterized by fever, myalgia, headache, and rash. SEVERE DENGUE is a more virulent form of dengue.
Dengue Vaccines
Vaccines or candidate vaccines used to prevent infection with DENGUE VIRUS. These include live-attenuated, subunit, DNA, and inactivated vaccines.
Year introduced: 2007
Severe Dengue
A virulent form of dengue characterized by THROMBOCYTOPENIA and an increase in vascular permeability (grades I and II) and distinguished by a positive pain test (e.g., TOURNIQUET PAIN TEST). When accompanied by SHOCK (grades III and IV), it is called dengue shock syndrome.
Year introduced: 1998
Dengue Virus
A species of the genus FLAVIVIRUS which causes an acute febrile and sometimes hemorrhagic disease in man. Dengue is mosquito-borne and four serotypes are known.
Year introduced: 1966
dengue-2 virus-induced cytotoxic factor [Supplementary Concept]
RN refers to strain D2-05; MW 43-45 kDa; isoelectric point 6.5; has been sequenced
Date introduced: June 22, 1994
glycoprotein E, dengue virus type 4 [Supplementary Concept]
Date introduced: October 23, 2002
dengue virus receptor [Supplementary Concept]
Date introduced: April 17, 1998
prM protein, Dengue virus type 3 [Supplementary Concept]
amino acid sequence given in first source; sequences known for H87 and 1153 strains
Date introduced: December 10, 1993
NS1 protein, Dengue virus type 2 [Supplementary Concept]
amino acid sequence given in first source; non-structural protein expressed in a baculovirus vector system
Date introduced: February 19, 1993
NS4B protein, Dengue virus [Supplementary Concept]
encodes a membrane protein that functions in virus replication and interference with host innate immunity; RefSeq NC_001475 (Type 3)
Date introduced: September 14, 2018
NS1 protein, Dengue virus type 4 [Supplementary Concept]
Date introduced: June 30, 2017
NS5 protein, dengue virus [Supplementary Concept]
Date introduced: July 15, 2013
E protein, Dengue virus type 3 [Supplementary Concept]
E protein TH Sman, Dengue virus [Supplementary Concept]
amino acid sequence given in first source
Date introduced: February 17, 1992
E-glycoprotein, Dengue virus type 2 [Supplementary Concept]
MW 53-55 kD; major glycoprotein in lipid envelope; monoclonal antibodies against DEN E-gp protect mice against dengue infection
Date introduced: April 16, 1987
nonstructural protein 2B, Dengue virus [Supplementary Concept]
Date introduced: March 31, 2021
nonstructural protein 2A, Dengue virus [Supplementary Concept]
NS4A protein, Dengue virus [Supplementary Concept]
Date introduced: September 10, 2015
NS1 protein, Dengue virus type 3 [Supplementary Concept]
GenBank FJ481174
Date introduced: January 6, 2010
ChimeriVax-DEN4 vaccine [Supplementary Concept]
Date introduced: May 15, 2008