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Alzheimer Disease
A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
Year introduced: 1998(1963)
Alzheimer disease, familial, type 3 [Supplementary Concept]
Alzheimer disease type 2 [Supplementary Concept]
Alzheimer disease type 4 [Supplementary Concept]
Alzheimer disease type 1 [Supplementary Concept]
Alzheimer Disease 12 [Supplementary Concept]
Alzheimer Disease 5 [Supplementary Concept]
Alzheimer Disease 10 [Supplementary Concept]
Alzheimer Disease 6 [Supplementary Concept]
PROM
Alzheimer Disease 7 [Supplementary Concept]
Alzheimer Disease 11 [Supplementary Concept]
Alzheimer Disease 8 [Supplementary Concept]
Alzheimer Disease 9 [Supplementary Concept]
APP protein, human [Supplementary Concept]
RefSeq NM_000484
Alzheimer Disease 16 [Supplementary Concept]
Alzheimer Disease 13 [Supplementary Concept]
Alzheimer Disease 14 [Supplementary Concept]
Alzheimer Disease 15 [Supplementary Concept]
Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy [Supplementary Concept]
Alzheimer Disease, Familial Early-Onset, With Coexisting Amyloid And Prion Pathology [Supplementary Concept]