Alu Elements
The Alu sequence family (named for the restriction endonuclease cleavage enzyme Alu I) is the most highly repeated interspersed repeat element in humans (over a million copies). It is derived from the 7SL RNA component of the SIGNAL RECOGNITION PARTICLE and contains an RNA polymerase III promoter. Transposition of this element into coding and regulatory regions of genes is responsible for many heritable diseases.
Year introduced: 1999
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Tree Number(s): G02.111.570.080.708.330.800.800.050, G05.360.080.708.330.800.800.050, G05.360.340.024.425.800.800.050
MeSH Unique ID: D020087
Entry Terms:
- Alu Element
- Element, Alu
- Elements, Alu
- Alu Family
- Alu Families
- Families, Alu
- Family, Alu
- Alu Repetitive Sequences
- Alu Repetitive Sequence
- Repetitive Sequence, Alu
- Repetitive Sequences, Alu
- Sequence, Alu Repetitive
- Sequences, Alu Repetitive
- Alu-Like Repetitive Sequence
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