Adenomatous Polyposis Coli - MeSH

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Items: 11

Select item 680111251.

A polyposis syndrome due to an autosomal dominant mutation of the APC genes (GENES, APC) on CHROMOSOME 5. The syndrome is characterized by the development of hundreds of ADENOMATOUS POLYPS in the COLON and RECTUM of affected individuals by early adulthood.

Year introduced: 1994

Select item 680256012.

Adenomatous Polyposis Coli Protein

A negative regulator of beta-catenin signaling which is mutant in ADENOMATOUS POLYPOSIS COLI and GARDNER SYNDROME.

Year introduced: 2002

Select item 674673233.

APC2 protein, Drosophila [Supplementary Concept]

involved in wingless signaling; amino acid sequence in first source

Date introduced: November 1, 2002

Select item 671180014.

APC protein, Drosophila [Supplementary Concept]

APC - adenomatous polyposis coli; amino acid sequence in first source; RefSeq NM_057804

Date introduced: March 29, 1999

Select item 671178465.

adenomatous polyposis coli protein 2 [Supplementary Concept]

homolog of ADENOMATOUS POLYPOSIS COLI PROTEIN; partial amino acid sequence in first source; GenBank AJ130783-96

Date introduced: March 22, 1999

Select item 680174916.

Genes, APC

Tumor suppressor genes located in the 5q21 region on the long arm of human chromosome 5. The mutation of these genes is associated with familial adenomatous polyposis (ADENOMATOUS POLYPOSIS COLI) and GARDNER SYNDROME, as well as some sporadic colorectal cancers.

Year introduced: 1993

Select item 675667787.

Adenomatous Polyposis Coli, Attenuated [Supplementary Concept]

Date introduced: November 5, 2012

Select item 675553378.

APC protein, human [Supplementary Concept]

RefSeq NM_000038

Date introduced: January 26, 2011

Select item 675171189.

AMER1 protein, human [Supplementary Concept]

RefSeq NM_152424

Date introduced: February 13, 2007