MeSH

An enzyme of the hydrolase class that catalyzes the reaction of triacylglycerol and water to yield diacylglycerol and a fatty acid anion. It is produced by glands on the tongue and by the pancreas and initiates the digestion of dietary fats. (From Dorland, 27th ed) EC 3.1.1.3.

Compounds that increase the enzymatic activity of LIPOPROTEIN LIPASE. Lipoprotein lipase activators have a potential role in the treatment of OBESITY by increasing LIPID METABOLISM. Note that substances that increase the synthesis of lipoprotein lipase are not included here.

Year introduced: 2011

An enzyme of the hydrolase class that catalyzes the reaction of triacylglycerol and water to yield diacylglycerol and a fatty acid anion. The enzyme hydrolyzes triacylglycerols in chylomicrons, very-low-density lipoproteins, low-density lipoproteins, and diacylglycerols. It occurs on capillary endothelial surfaces, especially in mammary, muscle, and adipose tissue. Genetic deficiency of the enzyme causes familial hyperlipoproteinemia Type I. (Dorland, 27th ed) EC 3.1.1.34.

Year introduced: HEPARIN-CLEARING FACTOR & LIPEMIA-CLEARING FACTOR were see under LIPOPROTEIN LIPASE 1963-1980

The severe infantile form of inherited lysosomal lipid storage diseases due to deficiency of acid lipase (STEROL ESTERASE). It is characterized by the accumulation of neutral lipids, particularly CHOLESTEROL ESTERS in leukocytes, fibroblasts, and hepatocytes. It is also known as Wolman's xanthomatosis and is an allelic variant of CHOLESTEROL ESTER STORAGE DISEASE.

Year introduced: 1989

An inherited condition due to a deficiency of either LIPOPROTEIN LIPASE or APOLIPOPROTEIN C-II (a lipase-activating protein). The lack of lipase activities results in inability to remove CHYLOMICRONS and TRIGLYCERIDES from the blood which has a creamy top layer after standing.

Year introduced: 2007 (1980)

An enzyme that catalyzes the hydrolysis of CHOLESTEROL ESTERS and some other sterol esters, to liberate cholesterol plus a fatty acid anion.

Year introduced: 2008(1975)

highly homologous to human pancreatic lipase (hPL), but its lipolytic activity is profoundly different from hPL

Date introduced: September 5, 1992

RefSeq NM_000236 (LIPC) and NM_139248 (LIPH)

Date introduced: November 3, 2005

An enzyme that catalyzes the hydrolysis of glycerol monoesters of long-chain fatty acids EC 3.1.1.23.

Year introduced: 1991(1975)

Date introduced: August 25, 2010

extracellular lipase from G. candidum; lipolytic enzyme that catalyzes the hydrolysis of triglycerols; fully characterized in first source; GenBank D00697

Date introduced: October 5, 1990

RefSeq NM_174103 (Bos taurus)

Date introduced: November 19, 1984

a triglyceride lipase; RefSeq NM_001012741

Date introduced: July 29, 2005

a triglyceride lipase; RefSeq NM_010720

Date introduced: July 29, 2005

selectively catalyzes the hydrolysis at the C-3 acetate in diester 11 and at C-5 position in diester 14

Date introduced: May 16, 2002

BUS = BulboUrethral gland Secretion; a 55-60 kDa pancreatic lipase-related protein (50-70% homology with pancreatic lipases); involved in the deterioration of goat spermatozoa in skimmed milk-based extenders as a result of oleic acid release

Date introduced: April 15, 1998

isolated from Pseudomonas; has been sequenced

Date introduced: August 29, 1994

catalyzes hydrolysis of 2-position ester bonds of triglycerides; isolated from Geotrichum candidum

Date introduced: March 8, 1994

from human (hPLRP2) & guinea pig (gPLRP2); highly homologous to human pancreatic lipase (hPL), but its lipolytic activity is profoundly different from hPL; amino acid sequence has been determined; RefSeq NM_005396 (human)

Date introduced: September 5, 1992

Date introduced: March 11, 1988