Gabexate

A serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inhibits the hydrolytic effects of thrombin, plasmin, and kallikrein, but not of chymotrypsin and aprotinin.

Year introduced: 1992

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Tree Number(s): D02.078.370.380

MeSH Unique ID: D016670

Registry Number: 4V7M9137X9

Entry Terms:

• Foy
• Gabexate Methanesulfonate
• Methanesulfonate, Gabexate
• Gabexate Mesilate
• Mesilate, Gabexate
• Gabexate Mesylate
• Mesylate, Gabexate
• Gabexate Monomethanesulfonate, 14C-Labeled Cpd
• Gabexate Monomethanesulfonate, 14C Labeled Cpd
• Gabexate Monomethanesulfonate
• Monomethanesulfonate, Gabexate

Previous Indexing:

• Anticoagulants (1966-1991)
• Guanidines (1966-1991)
• Protease Inhibitors (1979-1989)
• Serine Proteinase Inhibitors (1990-1991)

Pharmacologic Action:

• Anticoagulants
• Serine Proteinase Inhibitors

All MeSH Categories
Chemicals and Drugs Category
Organic Chemicals
Amidines
Guanidines
Gabexate