MeSH

Specific proteins found in or on cells of progesterone target tissues that specifically combine with progesterone. The cytosol progesterone-receptor complex then associates with the nucleic acids to initiate protein synthesis. There are two kinds of progesterone receptors, A and B. Both are induced by estrogen and have short half-lives.

Year introduced: 1977
Date introduced: May 3, 1976

Cytoplasmic proteins that bind estrogens and migrate to the nucleus where they regulate DNA transcription. Evaluation of the state of estrogen receptors in breast cancer patients has become clinically important.

Year introduced: 1977
Date introduced: May 3, 1976

Tumors or cancer of the human BREAST.

Date introduced: January 1, 1999