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The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow.


Isolated Noncompaction of the Ventricular Myocardium

Rare congenital cardiomyopathies characterized by the lack of left ventricular myocardium compaction. The noncompaction results in numerous prominent trabeculations and a loose myocardial meshwork (spongy myocardium) in the LEFT VENTRICLE. Heterogeneous clinical features include diminished systolic function sometimes associated with left ventricular dilation, that presents either neonatally or progressively. Often, the RIGHT VENTRICLE is also affected. CONGESTIVE HEART FAILURE; PULMONARY EMBOLISM; and ventricular ARRHYTHMIA are commonly seen.

Year introduced: 2010


Myocardial Stunning

Prolonged dysfunction of the myocardium after a brief episode of severe ischemia, with gradual return of contractile activity.

Year introduced: 1994


Noncompaction of Left Ventricular Myocardium with Congenital Heart Defects [Supplementary Concept]

Congenital heart defects characterized by multiple prominent trabeculations and intertrabecular recesses in hypertrophied and hypokinetic segments of the left ventricle . It is thought to be caused by an intrauterine arrest of myocardial development without compaction of the loose myocardial meshwork. Can occur in isolation or in association with congenital heart disease; germline mutations in the DTNA gene have been identified for LVNC1 (OMIM: 604169).

Date introduced: November 5, 2012

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