Glucagon-Like Peptide 1

A peptide of 36 or 37 amino acids that is derived from PROGLUCAGON and mainly produced by the INTESTINAL L CELLS. GLP-1(1-37 or 1-36) is further N-terminally truncated resulting in GLP-1(7-37) or GLP-1-(7-36) which can be amidated. These GLP-1 peptides are known to enhance glucose-dependent INSULIN release, suppress GLUCAGON release and gastric emptying, lower BLOOD GLUCOSE, and reduce food intake.

Year introduced: 2006

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Tree Number(s): D06.472.317.680.500.500

MeSH Unique ID: D052216

Registry Number: 89750-14-1

Entry Terms:

• Glucagon Like Peptide 1
• GLP-1
• GLP 1
• Glucagon-Like Peptide-1

Pharmacologic Action:

• Incretins

All MeSH Categories
Chemicals and Drugs Category
Hormones, Hormone Substitutes, and Hormone Antagonists
Hormones
Gastrointestinal Hormones
Proglucagon
Glucagon-Like Peptides
Glucagon-Like Peptide 1
Liraglutide