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Rosette Formation

The in vitro formation of clusters consisting of a cell (usually a lymphocyte) surrounded by antigenic cells or antigen-bearing particles (usually erythrocytes, which may or may not be coated with antibody or antibody and complement). The rosette-forming cell may be an antibody-forming cell, a memory cell, a T-cell, a cell bearing surface cytophilic antibodies, or a monocyte possessing Fc receptors. Rosette formation can be used to identify specific populations of these cells.

Year introduced: 1978

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Subheadings:

Tree Number(s): E01.370.225.812.706, E05.200.812.706, E05.478.594.730

MeSH Unique ID: D012397

Entry Terms:

  • Formation, Rosette
  • Formations, Rosette
  • Rosette Formations
  • Immunocytoadherence
  • Immunocytoadherences

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