Mixed Connective Tissue Disease
A syndrome with overlapping clinical features of systemic lupus erythematosus, scleroderma, polymyositis, and Raynaud's phenomenon. The disease is differentially characterized by high serum titers of antibodies to ribonuclease-sensitive extractable (saline soluble) nuclear antigen and a speckled epidermal nuclear staining pattern on direct immunofluorescence.
Year introduced: 1979
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Subheadings:
Tree Number(s): C17.300.540
MeSH Unique ID: D008947
Entry Terms:
- MCTD
- Connective Tissue Disease, Mixed
- Sharp Syndrome
- Syndrome, Sharp
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