Ranibizumab
A recombinant humanized monoclonal antibody fragment that binds VEGF-A to prevent its binding to VEGFR-1 and VEGFR-2 receptors. This activity reduces vessel permeability and angiogenesis in the treatment of neovascular age-related MACULAR DEGENERATION.
Year introduced: 2016 (2005)
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Subheadings:
Tree Number(s): D12.776.124.486.485.114.224.060.868, D12.776.124.790.651.114.224.060.868, D12.776.377.715.548.114.224.200.868
MeSH Unique ID: D000069579
Registry Number: ZL1R02VT79
Entry Terms:
- RhuFab V2
- V2, RhuFab
- Lucentis
See Also:
Pharmacologic Action: