Interleukin-33
A member of the INTERLEUKIN-1 protein family involved in the maturation of TH2 CELLS and the activation of MAST CELLS; BASOPHILS; EOSINOPHILS and NK CELLS. It is also produced by ENDOTHELIAL CELLS; EPITHELIAL CELLS and FIBROBLASTS; where it can function as an alarmin to modulate immune and inflammatory responses to tissue damage.
Year introduced: 2016 (2005)
Date introduced: July 1, 2015
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Tree Number(s): D12.644.276.374.465.850, D12.776.467.374.465.850, D23.529.374.465.850
MeSH Unique ID: D000067596
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