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src Homology Domains

Regions of AMINO ACID SEQUENCE similarity in the SRC-FAMILY TYROSINE KINASES that fold into specific functional tertiary structures. The SH1 domain is a CATALYTIC DOMAIN. SH2 and SH3 domains are protein interaction domains. SH2 usually binds PHOSPHOTYROSINE-containing proteins and SH3 interacts with CYTOSKELETAL PROTEINS.

Year introduced: 1996

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Subheadings:

Tree Number(s): G02.111.570.820.709.275.750.500.750

MeSH Unique ID: D018909

Entry Terms:

  • Homology Domain, src
  • Homology Domains, src
  • src Homology Domain
  • SH Domains
  • SH Domain
  • SH1 Domain
  • SH1 Domains
  • SH2 Domain
  • SH2 Domains
  • src Homology Region 2 Domain
  • SH3 Domain
  • SH3 Domains

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