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rho-Associated Kinases

A group of intracellular-signaling serine threonine kinases that bind to RHO GTP-BINDING PROTEINS. They were originally found to mediate the effects of rhoA GTP-BINDING PROTEIN on the formation of STRESS FIBERS and FOCAL ADHESIONS. Rho-associated kinases have specificity for a variety of substrates including MYOSIN-LIGHT-CHAIN PHOSPHATASE and LIM KINASES.

Year introduced: 2008

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Subheadings:

Tree Number(s): D08.811.913.696.620.682.700.814, D12.644.360.590, D12.776.476.595

MeSH Unique ID: D054460

Registry Number: EC 2.7.11.1

Entry Terms:

  • rho Associated Kinases
  • rho-Associated Kinase
  • rho Associated Kinase
  • ROCK Protein Kinases
  • Protein Kinases, ROCK
  • rho-Associated Coiled-Coil Kinase
  • Coiled-Coil Kinase, rho-Associated
  • rho Associated Coiled Coil Kinase
  • rho-Kinase
  • rho Kinase
  • ROK Kinase
  • rho-Associated Kinase 1
  • rho Associated Kinase 1
  • ROCK-I Protein Kinase
  • ROCK I Protein Kinase
  • p160ROCK
  • rho-Associated Kinase beta
  • rho Associated Kinase beta
  • rho-Associated Protein Kinase beta
  • rho Associated Protein Kinase beta
  • rho-Associated Coiled-Coil Containing Protein Kinase 1
  • rho Associated Coiled Coil Containing Protein Kinase 1
  • rho-Associated Kinase 2
  • rho Associated Kinase 2
  • rho-Associated Kinase alpha
  • rho Associated Kinase alpha
  • rho-Associated Coiled-Coil Containing Protein Kinase 2
  • rho Associated Coiled Coil Containing Protein Kinase 2
  • ROCK-II Protein Kinase
  • ROCK II Protein Kinase
  • p160 rhoA-Binding Kinase ROKalpha
  • p160 rhoA Binding Kinase ROKalpha
  • rho-Associated Protein Kinase alpha
  • rho Associated Protein Kinase alpha

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