p300-CBP Transcription Factors
A family of histone acetyltransferases that is structurally-related to CREB-BINDING PROTEIN and to E1A-ASSOCIATED P300 PROTEIN. They function as transcriptional coactivators by bridging between DNA-binding TRANSCRIPTION FACTORS and the basal transcription machinery. They also modify transcription factors and CHROMATIN through ACETYLATION.
Year introduced: 2006(1994)
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Subheadings:
Tree Number(s): D08.811.913.050.134.415.500.575, D12.776.930.680
MeSH Unique ID: D050880
Registry Number: EC 2.3.1.48
Entry Terms:
- p300 CBP Transcription Factors
- Transcription Factors, p300-CBP
- p300-CBP Coactivator
- Coactivator, p300-CBP
- p300 CBP Coactivator
- p300-CBP Protein
- p300 CBP Protein