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p300-CBP Transcription Factors

A family of histone acetyltransferases that is structurally-related to CREB-BINDING PROTEIN and to E1A-ASSOCIATED P300 PROTEIN. They function as transcriptional coactivators by bridging between DNA-binding TRANSCRIPTION FACTORS and the basal transcription machinery. They also modify transcription factors and CHROMATIN through ACETYLATION.

Year introduced: 2006(1994)

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Tree Number(s): D08.811.913.050.134.415.500.575, D12.776.930.680

MeSH Unique ID: D050880

Registry Number: EC

Entry Terms:

  • Transcription Factors, p300-CBP
  • p300 CBP Transcription Factors
  • p300-CBP Coactivator
  • Coactivator, p300-CBP
  • p300 CBP Coactivator
  • p300-CBP Protein
  • p300 CBP Protein

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