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beta Karyopherins

Nucleocytoplasmic transport molecules that bind to ALPHA KARYOPHERINS in the CYTOSOL and are involved in transport of molecules through the NUCLEAR PORE COMPLEX. Once inside the CELL NUCLEUS beta karyopherins interact with RAN GTP-BINDING PROTEIN and dissociate from alpha karyopherins. Beta karyopherins bound to RAN GTP-BINDING PROTEIN are then re-transported to the cytoplasm where hydrolysis of the GTP of RAN GTP-BINDING PROTEIN causes release of karyopherin beta.

Year introduced: 2002

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Subheadings:

Tree Number(s): D12.776.157.530.750.500.249, D12.776.543.585.750.500.249, D12.776.660.502.500

MeSH Unique ID: D028961

Entry Terms:

  • Karyopherins, beta
  • Kap95 protein
  • p92 nuclear protein
  • nuclear protein, p92
  • beta Importins
  • Importins, beta
  • Karyopherin-beta
  • Karyopherin-beta Subunit
  • Karyopherin beta Subunit
  • Importin-beta
  • Importin beta
  • Karyopherin beta

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