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Zinc Fingers

Motifs in DNA- and RNA-binding proteins whose amino acids are folded into a single structural unit around a zinc atom. In the classic zinc finger, one zinc atom is bound to two cysteines and two histidines. In between the cysteines and histidines are 12 residues which form a DNA binding fingertip. By variations in the composition of the sequences in the fingertip and the number and spacing of tandem repeats of the motif, zinc fingers can form a large number of different sequence specific binding sites.

Year introduced: 1991

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Tree Number(s): G02.111.570.820.709.275.500.985

MeSH Unique ID: D016335

Entry Terms:

  • Fingers, Zinc
  • Finger, Zinc
  • Zinc Finger
  • Zinc Finger Motifs
  • Motifs, Zinc Finger
  • Motif, Zinc Finger
  • Zinc Finger Motif
  • Zinc Finger DNA-Binding Domains
  • Zinc Finger DNA Binding Domains

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