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Wnt Proteins

Wnt proteins are a large family of secreted glycoproteins that play essential roles in EMBRYONIC AND FETAL DEVELOPMENT, and tissue maintenance. They bind to FRIZZLED RECEPTORS and act as PARACRINE PROTEIN FACTORS to initiate a variety of SIGNAL TRANSDUCTION PATHWAYS. The canonical Wnt signaling pathway stabilizes the transcriptional coactivator BETA CATENIN.

Year introduced: 2006(1987)

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Subheadings:

Tree Number(s): D12.776.467.984, D23.529.984

MeSH Unique ID: D051153

Entry Terms:

  • Wnt Factors
  • Wingless Type Proteins

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