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Vascular Endothelial Growth Factor A

The original member of the family of endothelial cell growth factors referred to as VASCULAR ENDOTHELIAL GROWTH FACTORS. Vascular endothelial growth factor-A was originally isolated from tumor cells and referred to as "tumor angiogenesis factor" and "vascular permeability factor". Although expressed at high levels in certain tumor-derived cells it is produced by a wide variety of cell types. In addition to stimulating vascular growth and vascular permeability it may play a role in stimulating VASODILATION via NITRIC OXIDE-dependent pathways. Alternative splicing of the mRNA for vascular endothelial growth factor A results in several isoforms of the protein being produced.

Year introduced: 2004

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Subheadings:

Tree Number(s): D12.644.276.100.800.200, D12.776.467.100.800.200, D23.529.100.800.200

MeSH Unique ID: D042461

Entry Terms:

  • Vascular Endothelial Growth Factor-A
  • VEGF-A
  • Vasculotropin
  • VEGF
  • Vascular Endothelial Growth Factor
  • Vascular Permeability Factor
  • Permeability Factor, Vascular
  • Glioma-Derived Vascular Endothelial Cell Growth Factor
  • Glioma Derived Vascular Endothelial Cell Growth Factor
  • GD-VEGF

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