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Vaccines, DNA

Recombinant DNA vectors encoding antigens administered for the prevention or treatment of disease. The host cells take up the DNA, express the antigen, and present it to the immune system in a manner similar to that which would occur during natural infection. This induces humoral and cellular immune responses against the encoded antigens. The vector is called naked DNA because there is no need for complex formulations or delivery agents; the plasmid is injected in saline or other buffers.

Year introduced: 1997

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Subheadings:

Tree Number(s): D12.776.828.868.910, D20.215.894.865.910, D23.050.865.910

MeSH Unique ID: D019444

Entry Terms:

  • Recombinant DNA Vaccines
  • DNA Vaccines, Recombinant
  • DNA Vaccines
  • Naked DNA Vaccines
  • DNA Vaccines, Naked
  • Vaccines, Naked DNA
  • Vaccines, Recombinant DNA
  • Polynucleotide Vaccines
  • Vaccines, Polynucleotide
  • Nucleic Acid Vaccines
  • Vaccines, Nucleic Acid

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