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Troponin C

A TROPONIN complex subunit that binds calcium and help regulate calcium-dependent muscle contraction. There are two troponin C subtypes: troponin C1 and C2. Troponin C1 is skeletal and cardiac type whereas troponin C2 is skeletal type. Troponin C1 is a BIOMARKER for damaged or injured CARDIAC MYOCYTES and mutations in troponin C1 gene are associated with FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.

Year introduced: 1997

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Subheadings:

Tree Number(s): D05.500.945.900, D05.750.078.730.825.900, D12.776.157.125.900, D12.776.210.500.910.900, D12.776.220.525.825.900

MeSH Unique ID: D019209

Entry Terms:

  • Troponin-C
  • Troponin C1
  • Troponin C2

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