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Transforming Growth Factors

Hormonally active polypeptides that can induce the transformed phenotype when added to normal, non-transformed cells. They have been found in culture fluids from retrovirally transformed cells and in tumor-derived cells as well as in non-neoplastic sources. Their transforming activities are due to the simultaneous action of two otherwise unrelated factors, TRANSFORMING GROWTH FACTOR ALPHA and TRANSFORMING GROWTH FACTOR BETA.

Year introduced: 1989

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Tree Number(s): D12.644.276.963, D12.776.467.960, D23.529.960

MeSH Unique ID: D015291

Registry Number: 76057-06-2

Entry Terms:

  • Factors, Transforming Growth
  • Growth Factors, Transforming
  • Transforming Growth Factor
  • Factor, Transforming Growth
  • Growth Factor, Transforming

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