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Transforming Growth Factor beta2

A TGF-beta subtype that was originally identified as a GLIOBLASTOMA-derived factor which inhibits the antigen-dependent growth of both helper and CYTOTOXIC T LYMPHOCYTES. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta2 and TGF-beta2 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor.

Year introduced: 2007(2000)

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Tree Number(s): D12.644.276.374.687.200, D12.644.276.954.775.200, D12.776.467.374.687.200, D12.776.467.942.775.200, D23.529.374.687.200, D23.529.942.775.200

MeSH Unique ID: D053781

Entry Terms:

  • Glioblastoma-Derived T-Cell Suppressor Factor
  • Glioblastoma Derived T Cell Suppressor Factor
  • Cartilage-Inducing Factor-B
  • Cartilage Inducing Factor B
  • Polyergin
  • TGF-beta2
  • TGF-beta-2
  • BSC-1 Cell Growth Inhibitor
  • BSC 1 Cell Growth Inhibitor
  • Suppressor Factor, T-Cell, Glioblastoma-Derived
  • Transforming Growth Factor beta 2 Latency Associated Peptide
  • TGF-beta2LAP
  • TGF beta2LAP
  • TGF-beta2 Latency-Associated Protein
  • Latency-Associated Protein, TGF-beta2
  • TGF beta2 Latency Associated Protein

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