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Tissue Inhibitor of Metalloproteinases

A family of secreted protease inhibitory proteins that regulates the activity of SECRETED MATRIX METALLOENDOPEPTIDASES. They play an important role in modulating the proteolysis of EXTRACELLULAR MATRIX, most notably during tissue remodeling and inflammatory processes.

Year introduced: 1998

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Tree Number(s): D12.776.645.875

MeSH Unique ID: D019714

Entry Terms:

  • Metalloproteinases Tissue Inhibitor
  • TIMP Proteins
  • Proteins, TIMP

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Pharmacologic Action:

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