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T-Lymphocytes, Cytotoxic

Immunized T-lymphocytes which can directly destroy appropriate target cells. These cytotoxic lymphocytes may be generated in vitro in mixed lymphocyte cultures (MLC), in vivo during a graft-versus-host (GVH) reaction, or after immunization with an allograft, tumor cell or virally transformed or chemically modified target cell. The lytic phenomenon is sometimes referred to as cell-mediated lympholysis (CML). These CD8-positive cells are distinct from NATURAL KILLER CELLS and NATURAL KILLER T-CELLS. There are two effector phenotypes: TC1 and TC2.

Year introduced: 1990

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Tree Number(s): A11.118.637.555.283.875, A11.118.637.555.567.550.500.200, A11.118.637.555.567.569.220.200, A11.118.637.555.567.569.500.200, A15.145.229.637.555.283.875, A15.145.229.637.555.567.550.500.200, A15.145.229.637.555.567.569.220.200, A15.145.229.637.555.567.569.500.200, A15.382.490.555.283.875, A15.382.490.555.567.550.500.200, A15.382.490.555.567.569.220.200, A15.382.490.555.567.569.500.200

MeSH Unique ID: D013602

Entry Terms:

  • Cytotoxic T-Lymphocyte
  • T Lymphocytes, Cytotoxic
  • T-Lymphocyte, Cytotoxic
  • Cell-Mediated Lympholytic Cells
  • Cell Mediated Lympholytic Cells
  • Cell, Cell-Mediated Lympholytic
  • Cell-Mediated Lympholytic Cell
  • Lympholytic Cell, Cell-Mediated
  • Lympholytic Cells, Cell-Mediated
  • Cytotoxic T-Lymphocytes
  • Cytotoxic T Cells
  • Cytotoxic T Cell
  • T Cell, Cytotoxic
  • Cytotoxic T Lymphocyte
  • Cytotoxic T Lymphocytes
  • Lymphocyte, Cytotoxic T
  • T Lymphocyte, Cytotoxic
  • TC2 Cells
  • TC2 Cell
  • Cell, TC2
  • TC1 Cells
  • TC1 Cell
  • Cell, TC1

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