Send to:

Choose Destination


Microbial antigens that have in common an extremely potent activating effect on T-cells that bear a specific variable region. Superantigens cross-link the variable region with class II MHC proteins regardless of the peptide binding in the T-cell receptor's pocket. The result is a transient expansion and subsequent death and anergy of the T-cells with the appropriate variable regions.

Year introduced: 1994

PubMed search builder options


Tree Number(s): D23.050.820

MeSH Unique ID: D018089

Previous Indexing:

See Also:

Supplemental Content

Loading ...
Support Center