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Sulindac

A sulfinylindene derivative prodrug whose sulfinyl moiety is converted in vivo to an active NSAID analgesic. Specifically, the prodrug is converted by liver enzymes to a sulfide which is excreted in the bile and then reabsorbed from the intestine. This helps to maintain constant blood levels with reduced gastrointestinal side effects.

Year introduced: 1990(1979)

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Subheadings:

Tree Number(s): D02.455.426.559.847.486.875, D04.615.486.875

MeSH Unique ID: D013467

Registry Number: 184SNS8VUH

Entry Terms:

  • Apo-Sulin
  • Apo Sulin
  • Arthrobid
  • Clinoril
  • Arthrocine
  • Klinoril
  • Sulindal
  • Chibret
  • Kenalin
  • MK-231
  • MK 231
  • MK231
  • Novo-Sundac
  • Novo Sundac
  • Nu-Sulindac
  • Nu Sulindac
  • Aclin
  • Copal

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