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Spironolactone

A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)

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Subheadings:

Tree Number(s): D02.540.679, D04.210.500.745.745.855

MeSH Unique ID: D013148

Registry Number: 27O7W4T232

Entry Terms:

  • Spirolactone
  • Veroshpiron
  • Verospirone
  • Spiractin
  • Spirobeta
  • Spirogamma
  • Spirolang
  • Spirono-Isis
  • Spirono Isis
  • Spironone
  • Spirospare
  • Aldactone
  • Verospiron
  • Aldactone A
  • Aquareduct
  • Duraspiron
  • Espironolactona Alter
  • Espironolactona Mundogen
  • Flumach
  • Frumikal
  • Jenaspiron
  • Novo-Spiroton
  • Novo Spiroton
  • NovoSpiroton
  • Practon
  • SC-9420
  • SC 9420
  • SC9420
  • Spiro L.U.T.
  • Spiro Von Ct
  • Ct, Spiro Von
  • Von Ct, Spiro

Pharmacologic Action:

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