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Sphingomyelin Phosphodiesterase

An enzyme that catalyzes the hydrolysis of sphingomyelin to ceramide (N-acylsphingosine) plus choline phosphate. A defect in this enzyme leads to NIEMANN-PICK DISEASE. EC 3.1.4.12.

Year introduced: 1991(1975)

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Subheadings:

Tree Number(s): D08.811.277.352.640.750

MeSH Unique ID: D013108

Registry Number: EC 3.1.4.12

Entry Terms:

  • Sphingomyelin Cleaving Enzyme
  • Sphingomyelinase C
  • Sphingomyelinase
  • Sphingomyelin Cholinephosphohydrolase

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