Sp1 Transcription Factor

Promoter-specific RNA polymerase II transcription factor that binds to the GC box, one of the upstream promoter elements, in mammalian cells. The binding of Sp1 is necessary for the initiation of transcription in the promoters of a variety of cellular and viral GENES.

Year introduced: 2006(1991)

Date introduced: June 19, 1990

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Tree Number(s): D12.776.260.522.750.249, D12.776.930.375.750.249

MeSH Unique ID: D016329

Entry Terms:

• Specificity Protein 1 Transcription Factor
• Transcription Factor, Sp1

Previous Indexing:

• DNA-Binding Proteins (1986-1990)
• Transcription Factors (1986-1990)

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
DNA-Binding Proteins
Kruppel-Like Transcription Factors
Sp Transcription Factors
Sp1 Transcription Factor

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Transcription Factors
Kruppel-Like Transcription Factors
Sp Transcription Factors
Sp1 Transcription Factor