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Sp1 Transcription Factor

Promoter-specific RNA polymerase II transcription factor that binds to the GC box, one of the upstream promoter elements, in mammalian cells. The binding of Sp1 is necessary for the initiation of transcription in the promoters of a variety of cellular and viral GENES.

Year introduced: 2006(1991)

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Tree Number(s): D12.776.260.522.750.249, D12.776.930.375.750.249

MeSH Unique ID: D016329

Entry Terms:

  • Transcription Factor, Sp1
  • Specificity Protein 1 Transcription Factor

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