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A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator.

Year introduced: HYDROXYTRYPTAMINE was see SEROTONIN 1975-1992

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Tree Number(s): D02., D03.633.100.473.914.814, D23.469.050.650

MeSH Unique ID: D012701

Registry Number: 333DO1RDJY

Entry Terms:

  • 5-Hydroxytryptamine
  • 5 Hydroxytryptamine
  • Hippophaine
  • 3-(2-Aminoethyl)-1H-indol-5-ol
  • Enteramine
  • 5-HT
  • Hydroxytryptamine

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Pharmacologic Action:

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