Serotonin

A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator.

Year introduced: HYDROXYTRYPTAMINE was see SEROTONIN 1975-1992

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Do not include MeSH terms found below this term in the MeSH hierarchy.

Tree Number(s): D02.092.211.215.801.852, D03.633.100.473.914.814, D23.469.050.650

MeSH Unique ID: D012701

Registry Number: 333DO1RDJY

Entry Terms:

• 5-HT
• 5-Hydroxytryptamine
• 5 Hydroxytryptamine
• 3-(2-Aminoethyl)-1H-indol-5-ol
• Enteramine
• Hippophaine
• Hydroxytryptamine

See Also:

• Receptors, Serotonin
• Serotonin Agents
• Serotonin Syndrome

Pharmacologic Action:

• Serotonin Receptor Agonists

All MeSH Categories
Chemicals and Drugs Category
Organic Chemicals
Amines
Biogenic Amines
Biogenic Monoamines
Tryptamines
Serotonin
5-Methoxytryptamine

All MeSH Categories
Chemicals and Drugs Category
Heterocyclic Compounds
Heterocyclic Compounds, Fused-Ring
Heterocyclic Compounds, 2-Ring
Indoles
Tryptamines
Serotonin
5-Methoxytryptamine
Bufotenin
Methoxydimethyltryptamines

All MeSH Categories
Chemicals and Drugs Category
Biological Factors
Inflammation Mediators
Autacoids
Serotonin