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Self Tolerance

The normal lack of the ability to produce an immunological response to autologous (self) antigens. A breakdown of self tolerance leads to autoimmune diseases. The ability to recognize the difference between self and non-self is the prime function of the immune system.

Year introduced: 1994

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Subheadings:

Tree Number(s): G12.535.425.800

MeSH Unique ID: D017634

Entry Terms:

  • Self Tolerances
  • Tolerance, Self
  • Tolerances, Self

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