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STAT5 Transcription Factor

A signal transducer and activator of transcription that mediates cellular responses to a variety of CYTOKINES. Stat5 activation is associated with transcription of CELL CYCLE regulators such as CYCLIN KINASE INHIBITOR P21 and anti-apoptotic genes such as BCL-2 GENES. Stat5 is constitutively activated in many patients with acute MYELOID LEUKEMIA.

Year introduced: 2006(1992)

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Subheadings:

Tree Number(s): D12.644.360.024.342.500, D12.776.157.057.186.500, D12.776.476.024.430.500, D12.776.930.840.500

MeSH Unique ID: D050799

Entry Terms:

  • Factor, STAT5 Transcription
  • Transcription Factor, STAT5
  • STAT5 Protein
  • Signal Transducer and Activator of Transcription 5
  • STAT5b Transcription Factor
  • Transcription Factor, STAT5b
  • STAT5beta Protein
  • STAT5b Protein
  • Signal Transducer and Activator of Transcription 5B
  • STAT5a Transcription Factor
  • Transcription Factor, STAT5a
  • Mammary Gland Factor
  • Signal Transducer and Activator of Transcription 5A
  • STAT5alpha Protein
  • STAT5a Protein
  • Mammary Gland-Specific Nuclear Factor
  • Mammary Gland Specific Nuclear Factor

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