Ribonucleoprotein, U1 Small Nuclear

A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the U1 snRNP along with other small nuclear ribonucleoproteins (U2, U4-U6, and U5) assemble into SPLICEOSOMES that remove introns from pre-mRNA by splicing. The U1 snRNA forms base pairs with conserved sequence motifs at the 5'-splice site and recognizes both the 5'- and 3'-splice sites and may have a fundamental role in aligning the two sites for the splicing reaction.

Year introduced: 2000

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Tree Number(s): D12.776.157.725.500.875.600, D12.776.157.725.829.313, D12.776.664.962.500.875.600, D12.776.664.962.829.313

MeSH Unique ID: D017412

Entry Terms:

• Small Nuclear Ribonucleoproteins, U1
• U1 Small Nuclear Ribonucleoproteins
• U1 snRNP
• Ribonucleoproteins, Small, U1

Previous Indexing:

• Ribonucleoproteins (1975-1992)

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Carrier Proteins
RNA-Binding Proteins
Ribonucleoproteins
Ribonucleoproteins, Small Nuclear
Ribonucleoprotein, U1 Small Nuclear

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Carrier Proteins
RNA-Binding Proteins
RNA Splicing Factors
Ribonucleoprotein, U1 Small Nuclear

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Nucleoproteins
RNA-Binding Proteins
Ribonucleoproteins
Ribonucleoproteins, Small Nuclear
Ribonucleoprotein, U1 Small Nuclear

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Nucleoproteins
RNA-Binding Proteins
RNA Splicing Factors
Ribonucleoprotein, U1 Small Nuclear