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Retinoblastoma-Like Protein p130

A negative regulator of the CELL CYCLE that undergoes PHOSPHORYLATION by CYCLIN-DEPENDENT KINASES. RBL2 contains a conserved pocket region that binds E2F4 TRANSCRIPTION FACTOR and E2F5 TRANSCRIPTION FACTOR. RBL2 also interacts with viral ONCOPROTEINS such as POLYOMAVIRUS TUMOR ANTIGENS; ADENOVIRUS E1A PROTEINS; and PAPILLOMAVIRUS E7 PROTEINS.

Year introduced: 2006(1994)

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Subheadings:

Tree Number(s): D12.776.624.776.735, D12.776.660.794, D12.776.744.755

MeSH Unique ID: D050717

Entry Terms:

  • p130, Retinoblastoma-Like Protein
  • Retinoblastoma Like Protein p130
  • Retinoblastoma-Like Protein 2
  • Retinoblastoma Like Protein 2
  • RBL2 Protein

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