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Receptors, Tumor Necrosis Factor, Member 14

A novel member of the tumor-necrosis factor receptor family that can also mediate HERPES SIMPLEX VIRUS TYPE 1 entry into cells. It has specificity for TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 14 and the homotrimeric form of LYMPHOTOXIN-ALPHA. The receptor is abundantly expressed on T-LYMPHOCYTES and may play a role in regulating lymphocyte activation. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.

Year introduced: 2007(1997)

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Tree Number(s): D12.776.543.750.705.852.760.500, D12.776.543.750.830.850

MeSH Unique ID: D053240

Entry Terms:

  • HveA Protein
  • Tumor Necrosis Factor Receptor Superfamily, Member 14
  • Tumor Necrosis Factor Receptor Subfamily, Member 14
  • HVEM Protein
  • Herpesvirus Entry Mediator
  • Entry Mediator, Herpesvirus

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