Receptors, GABA
Cell-surface proteins that bind GAMMA-AMINOBUTYRIC ACID with high affinity and trigger changes that influence the behavior of cells. GABA-A receptors control chloride channels formed by the receptor complex itself. They are blocked by bicuculline and usually have modulatory sites sensitive to benzodiazepines and barbiturates. GABA-B receptors act through G-proteins on several effector systems, are insensitive to bicuculline, and have a high affinity for L-baclofen.
Year introduced: 1994
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Subheadings:
Tree Number(s): D12.776.543.750.720.200.300
MeSH Unique ID: D018079
Entry Terms:
- GABA Receptors
- gamma-Aminobutyric Acid Receptor
- gamma Aminobutyric Acid Receptor
- Receptor, gamma-Aminobutyric Acid
- gamma-Aminobutyric Acid Receptors
- gamma Aminobutyric Acid Receptors
- Receptors, gamma-Aminobutyric Acid
- Receptors, gamma Aminobutyric Acid
- GABA Receptor
- Receptor, GABA
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