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Receptor, IGF Type 1

A protein-tyrosine kinase receptor that is closely related in structure to the INSULIN RECEPTOR. Although commonly referred to as the IGF-I receptor, it binds both IGF-I and IGF-II with high affinity. It is comprised of a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precursor protein. The beta subunit contains an intrinsic tyrosine kinase domain.

Year introduced: 2000(1993)

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Subheadings:

Tree Number(s): D08.811.913.696.620.682.725.400.185, D12.776.543.750.630.468, D12.776.543.750.750.400.780.400

MeSH Unique ID: D017526

Registry Number: EC 2.7.10.1

Entry Terms:

  • Receptors, IGF-1
  • IGF-1 Receptors
  • Receptors, IGF 1
  • IGF-1 Receptor
  • IGF 1 Receptor
  • Receptor, IGF-1
  • Receptors, Insulin-Like-Growth Factor I
  • IGF-I Receptor
  • IGF I Receptor
  • Receptor, Insulin-Like Growth Factor Type 1
  • Receptor, IGF-I
  • Receptor, IGF I
  • Receptor, Insulin-Like Growth Factor I
  • Insulin-Like-Growth Factor I Receptor
  • Insulin Like Growth Factor I Receptor
  • IGF Type 1 Receptor
  • Receptor, IGF Type 1 beta Subunit
  • Receptor, IGF Type 1 alpha Subunit

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