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Receptor, Fibroblast Growth Factor, Type 2

A fibroblast growth factor receptor which contains three extracellular IMMUNOGLOBULIN I-SET DOMAINS and is expressed as two isoforms. One receptor isoform is expressed in the MESENCHYME and is activated by FIBROBLAST GROWTH FACTOR 2. A second isoform is expressed mainly by EPITHELIAL CELLS and is activated by FIBROBLAST GROWTH FACTOR 7 and FIBROBLAST GROWTH FACTOR 10. Mutation of the gene for fibroblast growth factor receptor 2 can result in craniosynostotic syndromes (e.g., APERT SYNDROME; and CROUZON SYNDROME).

Year introduced: 2006(1999)

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Subheadings:

Tree Number(s): D08.811.913.696.620.682.725.400.178, D12.776.543.750.630.441, D12.776.543.750.750.400.370.750

MeSH Unique ID: D051497

Registry Number: EC 2.7.10.1

Entry Terms:

  • BEK Fibroblast Growth Factor Receptor
  • BEK Protein Tyrosine Kinase
  • Bek Fgf Receptor Kinase
  • Fibroblast Growth Factor Receptor 2
  • Bek-Related Fibroblast Growth Factor-Receptor-1
  • Bek Related Fibroblast Growth Factor Receptor 1
  • Fibroblast Growth Factor Receptors 2
  • FGFR2 Protein
  • CD332 Antigen
  • Antigen, CD332
  • BEK Fibroblast Growth Factor Receptor Kinase
  • Fibroblast Growth Factor Receptor 2c
  • Receptor, Fibroblast Growth Factor 2c
  • FGFR2c
  • Fibroblast Growth Factor Receptor 2b
  • Receptor, Fibroblast Growth Factor 2b
  • FGFR2b
  • Fibroblast Growth Factor Receptors 2b

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