U.S. flag

An official website of the United States government


Send to:

Choose Destination

Proto-Oncogene Proteins c-abl

Non-receptor tyrosine kinases encoded by the C-ABL GENES. They are distributed in both the cytoplasm and the nucleus. c-Abl plays a role in normal HEMATOPOIESIS especially of the myeloid lineage. Oncogenic transformation of c-abl arises when specific N-terminal amino acids are deleted, releasing the kinase from negative regulation.

Year introduced: 1991

PubMed search builder options


Tree Number(s): D08.811.913.696.620.682.725.500, D12.776.476.568.500, D12.776.624.664.700.167

MeSH Unique ID: D016315

Registry Number: EC

Entry Terms:

  • c-abl, Proto-Oncogene Proteins
  • Proto Oncogene Proteins c abl
  • abl Proto-Oncogene Products
  • abl Proto Oncogene Products
  • Products, abl Proto-Oncogene
  • Proto-Oncogene Products, abl
  • Proto-Oncogene Proteins abl
  • abl, Proto-Oncogene Proteins
  • Proteins abl, Proto-Oncogene
  • Proto Oncogene Proteins abl
  • abl Proto-Oncogene Proteins
  • abl Proto Oncogene Proteins
  • Proto-Oncogene Proteins, abl
  • c-abl Proteins
  • c abl Proteins

Previous Indexing:

See Also:

Supplemental Content

Loading ...