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Protein Tyrosine Phosphatase, Non-Receptor Type 2

A subtype of non-receptor protein tyrosine phosphatase that is closely-related to PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1. Alternative splicing of the mRNA for this phosphatase results in the production at two gene products, one of which includes a C-terminal nuclear localization domain that may be involved in the transport of the protein to the CELL NUCLEUS. Although initially referred to as T-cell protein tyrosine phosphatase the expression of this subtype occurs widely.

Year introduced: 2008(1994)

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Subheadings:

Tree Number(s): D08.811.277.352.650.775.300.200, D12.644.360.585.200, D12.776.476.564.200

MeSH Unique ID: D054578

Registry Number: EC 3.1.3.48

Entry Terms:

  • Protein Tyrosine Phosphatase, Non Receptor Type 2
  • TCPTP Enzyme
  • TC-PTP
  • T-Cell Protein Tyrosine Phosphatase
  • T Cell Protein Tyrosine Phosphatase
  • Protein Tyrosine Phosphatase, Non-Receptor Type 2, TC48 Isoform
  • TC48 Protein Tyrosine Phosphatase
  • TC48 Enzyme
  • Protein Tyrosine Phosphatase, Non-Receptor Type 2, TC45 Isoform
  • TC45 Protein Tyrosine Phosphatase
  • TC45 Enzyme

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