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Proteasome Endopeptidase Complex

A large multisubunit complex that plays an important role in the degradation of most of the cytosolic and nuclear proteins in eukaryotic cells. It contains a 700-kDa catalytic sub-complex and two 700-kDa regulatory sub-complexes. The complex digests ubiquitinated proteins and protein activated via ornithine decarboxylase antizyme.

Year introduced: 2005

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Subheadings:

Tree Number(s): D05.500.562.500, D08.811.277.656.918, D08.811.600.730

MeSH Unique ID: D046988

Registry Number: EC 3.4.25.1

Entry Terms:

  • Complex, Proteasome Endopeptidase
  • Endopeptidase Complex, Proteasome
  • Macropain
  • Macroxyproteinase
  • Multicatalytic Proteinase
  • Proteinase, Multicatalytic
  • Prosome
  • Proteasome
  • 20S Proteasome
  • Proteasome, 20S
  • Multicatalytic Endopeptidase Complex
  • Complex, Multicatalytic Endopeptidase
  • Endopeptidase Complex, Multicatalytic
  • Ingensin

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