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PrPC Proteins

Normal cellular isoform of PRION PROTEINS encoded by a chromosomal gene and found in normal and scrapie-infected brain tissue, and other normal tissue. PrPC are protease-sensitive proteins whose function is unknown. Posttranslational modification of PrPC into PrPSC leads to infectivity.

Year introduced: 1995

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Subheadings:

Tree Number(s): D12.776.785.340.500

MeSH Unique ID: D018621

Entry Terms:

  • PrP-sen
  • PrP sen
  • Cp 33-35
  • Scrapie Amyloid Precursor Protein
  • Cp33-35, Scrapie

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