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Polymyxin B

A mixture of polymyxins B1 and B2, obtained from BACILLUS POLYMYXA strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Polymyxin B is used for treatment of infections with gram-negative bacteria, but may be neurotoxic and nephrotoxic.

Year introduced: 1991(1978)

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Tree Number(s): D04.345.566.780.750, D10.477.750.750, D12.644.050.600.750, D12.644.641.780.750, D12.776.543.695.054.600.750

MeSH Unique ID: D011112

Registry Number: J2VZ07J96K

Entry Terms:

  • Polymyxin B Sulfate
  • Aerosporin

Pharmacologic Action:

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