Phosphatidylinositol 4,5-Diphosphate

A phosphoinositide present in all eukaryotic cells, particularly in the plasma membrane. It is the major substrate for receptor-stimulated phosphoinositidase C, with the consequent formation of inositol 1,4,5-triphosphate and diacylglycerol, and probably also for receptor-stimulated inositol phospholipid 3-kinase. (Kendrew, The Encyclopedia of Molecular Biology, 1994)

Year introduced: 1997

PubMed search builder options

Subheadings:

Restrict to MeSH Major Topic.

Do not include MeSH terms found below this term in the MeSH hierarchy.

Tree Number(s): D10.570.755.375.760.400.942.625.900

MeSH Unique ID: D019269

Entry Terms:

• 4,5-Diphosphate, Phosphatidylinositol
• Phosphatidylinositol 4,5 Diphosphate
• Phosphatidylinositol 4,5-Biphosphate
• 4,5-Biphosphate, Phosphatidylinositol
• Phosphatidylinositol 4,5 Biphosphate
• Phosphatidylinositol Phosphate, PtdIns(4,5)P2
• Phosphatidylinositol-4,5-Biphosphate
• PtdIns(4,5)P2
• PtdInsP2
• PtdInsP
• PtIns 4,5-P2

Previous Indexing:

• Phosphatidylinositol Phosphates (1994-1996)
• Phosphatidylinositols (1981-1993)

All MeSH Categories
Chemicals and Drugs Category
Lipids
Membrane Lipids
Phospholipids
Glycerophosphates
Phosphatidic Acids
Glycerophospholipids
Phosphatidylinositols
Phosphatidylinositol Phosphates
Phosphatidylinositol 4,5-Diphosphate