Phorbol 12,13-Dibutyrate

A phorbol ester found in CROTON OIL which, in addition to being a potent skin tumor promoter, is also an effective activator of calcium-activated, phospholipid-dependent protein kinase (protein kinase C). Due to its activation of this enzyme, phorbol 12,13-dibutyrate profoundly affects many different biological systems.

Year introduced: 1989

Date introduced: May 14, 1988

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Tree Number(s): D02.455.849.291.500.510.700

MeSH Unique ID: D015240

Registry Number: 37558-16-0

Entry Terms:

• 12,13-Dibutyrate, Phorbol
• Phorbol-12,13-Dibutyrate
• Phorbol 12,13 Dibutyrate

Previous Indexing:

• Phorbol Esters (1979-1988)

Pharmacologic Action:

• Carcinogens

All MeSH Categories
Chemicals and Drugs Category
Organic Chemicals
Hydrocarbons
Terpenes
Diterpenes
Phorbols
Phorbol Esters
Phorbol 12,13-Dibutyrate