ATP Binding Cassette Transporter, Subfamily B, Member 1
A 170-kDa transmembrane glycoprotein from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS. It serves as an ATP-dependent efflux pump for a variety of chemicals, including many ANTINEOPLASTIC AGENTS. Overexpression of this glycoprotein is associated with multidrug resistance (see DRUG RESISTANCE, MULTIPLE).
Year introduced: 2019 (1995)
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Subheadings:
Tree Number(s): D09.400.430.890.020.400.153, D12.776.157.530.100.075.063, D12.776.157.530.450.074.500.500.250.125, D12.776.395.550.020.400.153, D12.776.543.550.192.400.153, D12.776.543.585.100.200.125, D12.776.543.585.450.074.500.500.250.125
MeSH Unique ID: D020168
Entry Terms:
- ABCB1 Protein
- CD243 Antigen
- Antigen, CD243
- ATP Binding Cassette Transporter, Sub-Family B, Member 1
- P-Glycoprotein
- P Glycoprotein
- MDR1 Protein
- Multidrug Resistance Protein 1
- ATP-Binding Cassette, Sub-Family B, Member 1
- PGY-1 Protein
- PGY 1 Protein
- ATP-Dependent Translocase ABCB1
- ABCB1, ATP-Dependent Translocase
- ATP Dependent Translocase ABCB1
- Translocase ABCB1, ATP-Dependent
- MDR1B Protein
- Protein, MDR1B
- P-Glycoprotein 1
- 1, P-Glycoprotein
- P Glycoprotein 1
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