Osteoprotegerin

A secreted member of the TNF receptor superfamily that negatively regulates osteoclastogenesis. It is a soluble decoy receptor of RANK LIGAND that inhibits both CELL DIFFERENTIATION and function of OSTEOCLASTS by inhibiting the interaction between RANK LIGAND and RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B.

Year introduced: 2007(1997)

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Tree Number(s): D12.776.543.750.705.852.760.949.249

MeSH Unique ID: D053244

Entry Terms:

• Osteoclastogenesis Inhibitory Factor
• Receptors, Tumor Necrosis Factor, Member 11b
• Tumor Necrosis Factor Receptor 11b
• Tumor Necrosis Factor Receptor Superfamily, Member 11b
• FDCR-1 Protein
• FDCR 1 Protein
• OCIF Protein
• Follicular Dendritic Cell-Derived Receptor-1
• Follicular Dendritic Cell Derived Receptor 1

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Membrane Proteins
Receptors, Cell Surface
Receptors, Immunologic
Receptors, Cytokine
Receptors, Tumor Necrosis Factor
Tumor Necrosis Factor Decoy Receptors
Osteoprotegerin