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Oligonucleotide Probes

Synthetic or natural oligonucleotides used in hybridization studies in order to identify and study specific nucleic acid fragments, e.g., DNA segments near or within a specific gene locus or gene. The probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the probe include the radioisotope labels 32P and 125I and the chemical label biotin.

Year introduced: 1989

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Tree Number(s): D13.444.600.601, D27.505.259.750.600.650, D27.720.470.530.600.650

MeSH Unique ID: D015345

Entry Terms:

  • Probes, Oligonucleotide
  • Oligodeoxyribonucleotide Probes
  • Probes, Oligodeoxyribonucleotide
  • Oligoribonucleotide Probes
  • Probes, Oligoribonucleotide

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